Our Research Papers

Safety & anti-ulcerogenic activity of Clovinol®

Safety and anti-ulcerogenic activity of a novel polyphenol-rich extract of clove buds (Syzygium aromaticum L)

Journal of functional Foods, 2015

No of Subjects – Wistar rats

Dosage - Lethal dose oral administration - 5g

                 Sub-acute administration – 2.5g

Result – Result shown the safety and efficacy of Clovinol® as alcohol-induced stomach ulcer protective/ curative agent.

Clovinol® in different food matrices

Beyond the flavour: a de-flavoured polyphenol rich extract of clove buds (Syzygium aromaticum L) as a novel dietary antioxidant ingredient

Journal of food and function, 2015

No of subjects – 

Dosage – 250mg / day

Result – Supplementation of Clovinol® exhibited significant enhancement in endogenous cellular antioxidant enzyme levels.

Toxicity study of Clovinol®

Safety assessment of a standardized polyphenolic extract of clovebuds: Subchronic toxicity and mutagenicity studies

Journal of toxicology reports , 2016

No of subjects – 

Dosage - oral acute – 5g/Kg b.wt.

                 Subchronic (0.25, 0.5 and 1g/kg b.wt)

Result – Clovinol® is safe in rats and can be further considered for human consumption.

Hepato-protective effect of Clovinol®

Hepato-protective Effect of Clove Bud Polyphenols (Syzygium aromaticum L.) (Clovinol®) by Modulating Alcohol Induced Oxidative Stress and Inflammation

Journal of Food Research, 2017

No of subjects – 

Dosage – 100mg

Result – Supplementation of Clovinol® showed down regulation of alcohol-induced oxidative stress and thereby act as a potential functional ingredient for liver health

Clovinol® reduced alcohol-induced hangover

Clove Bud Polyphenols Alleviate Alterations in Inflammation and Oxidative Stress Markers Associated with Binge Drinking: A Randomized Double-Blinded Placebo-Controlled Crossover Study

Journal of medicinal food, 2018

No of subjects – 16

Dosage – 250mg / day

Result – Clovinol® was found to be safe and effective natural medicine for alcohol-induced toxicity and for reducing hangover.

Clovinol® maintains healthy glucose metabolism

Water-soluble polyphenol-rich clove extract lowers pre- and post-prandial blood glucose levels in healthy and prediabetic volunteers: an open label pilot study

Journal of BMC Complementary and Alternative Medicine, 2019

No of subjects – 13

Dosage – 250mg/ day

Result – Clovinol® was found to maintain healthy glucose metabolism